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Twice-daily dosing

How to take DUVYZAT

Twice-daily dosing
  • DUVYZAT is a liquid medicine that can be taken at home, twice a day
  • The starting dose for DUVYZAT is based on weight
Taking DUVYZAT
DUVYZAT can be used on its own or along with steroids. Talk to your healthcare provider about DUVYZAT and any other medications you or your loved one are taking. See full Important Safety Information.
Taking DUVYZAT
Ryan, taking DUVYZAT for 4+ years. Ryan, taking DUVYZAT for 4+ years.

Establish a daily routine with DUVYZAT

The three S's of success:

  • Same time

    (morning and night)

  • Set dose reminders

  • Snack on!

    (can be taken with food)

What to expect when starting DUVYZAT

Before starting DUVYZAT, your healthcare provider will perform some tests. These will include a blood test to check levels of platelets (tiny cell fragments that help blood clot) and triglycerides (a type of fat in your blood).

Your healthcare provider may also order an electrocardiogram (ECG). This is a simple test that checks how the heart is beating. This test is done if you or your loved one have an underlying heart condition or are taking medicines that might affect heart rhythm.

Susan, Ryan's mom
Susan, Ryan's mom.
Not an actual doctor.

Regular testing with DUVYZAT

Once you have started taking DUVYZAT, your healthcare provider will closely monitor your health through regular blood tests. This will allow your healthcare team to ensure DUVYZAT is working as expected. If side effects occur, contact your healthcare provider.

Blood tests you can expect after starting DUVYZAT:

  • Blood cell count (complete blood count [CBC] + differential) to check the levels of different types of cells in your blood
  • Triglycerides to check the level of a type of fat in your blood

Monitoring schedule

Month 1* 2* 3 4 5 6 7 8 9 10 11 12
Blood test
*Blood tests are every 2 weeks for the first 2 months.
These tests are more frequent at the beginning of treatment. Over time, they will become less frequent.
Clinical Trial Results Safety Information
More than 1000 people with Duchenne are currently being treated with DUVYZAT.‡ ‡Data as of July 2025.
Stories of Strength

Hear from people living with Duchenne and from healthcare providers at our DUVYZAT Stories of Strength events.

HEAR THEIR STORIES

Important Safety Information

What is the most important information I should know about DUVYZAT?

  • Low platelet counts in your blood (thrombocytopenia). Platelets are important for blood clotting, so having fewer can increase your risk of bleeding or bruising. Your doctor will check your blood count before you start DUVYZAT and regularly during treatment for signs of thrombocytopenia. Call your doctor right away if you notice unusual bleeding or small red or purple spots on the skin.
  • Increased levels of fat (triglycerides) in your blood. You may not have any symptoms, so your doctor will do blood tests before you start DUVYZAT and regularly during treatment to check your triglyceride levels.
  • Frequent watery loose stools (diarrhea) and vomiting. DUVYZAT can cause vomiting and moderate to severe diarrhea. If diarrhea occurs, you should keep track of the frequency and severity of your diarrhea symptoms, drink plenty of fluids, and contact your doctor.
  • If thrombocytopenia, increased triglycerides, or diarrhea cannot be managed, your doctor may change your dose or stop your treatment with DUVYZAT, if needed.

Before taking DUVYZAT, tell your doctor about all of your medical conditions, including:

  • any heart problems or medicines you take that could increase your chance for irregular heart rhythms.
  • any bleeding problems.

Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Taking DUVYZAT with certain other medicines may affect each other. Taking DUVYZAT with other medicines can cause serious side effects. Do not start or stop other medicines without talking to your doctor.

What are the possible side effects of DUVYZAT?

  • DUVYZAT can cause serious side effects, including changes in the electrical activity of your heart called QT prolongation. QT prolongation can increase the risk of developing a type of irregular heart rhythm known as Torsades de Pointes. Call your doctor right away if you feel faint, have an irregular heartbeat, feel dizzy, or lose consciousness. See the section titled “What is the most important information I should know about DUVYZAT?” for more information about side effects.

The most common side effects (occurring in >5% of DUVYZAT-treated patients) included diarrhea, abdominal pain, low platelet levels, nausea/vomiting, high triglyceride levels, elevated temperature/fever, muscle aches, rash, joint pain, fatigue, constipation and decreased appetite.

These are not all of the possible side effects of DUVYZAT. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is DUVYZAT?

DUVYZAT is a prescription medicine for the treatment of Duchenne muscular dystrophy (DMD) in people 6 years of age and older. It is not known if DUVYZAT is safe and effective in children under age 6.

Please see full Prescribing Information and Medication Guide.
More than 1000 people with Duchenne are currently being treated with DUVYZAT.‡ ‡Data as of July 2025.
Stories of Strength

Hear from people living with Duchenne and from healthcare providers at our DUVYZAT Stories of Strength events.

HEAR THEIR STORIES

Important Safety Information

What is the most important information I should know about DUVYZAT?

  • Low platelet counts in your blood (thrombocytopenia). Platelets are important for blood clotting, so having fewer can increase your risk of bleeding or bruising. Your doctor will check your blood count before you start DUVYZAT and regularly during treatment for signs of thrombocytopenia. Call your doctor right away if you notice unusual bleeding or small red or purple spots on the skin.
  • Increased levels of fat (triglycerides) in your blood. You may not have any symptoms, so your doctor will do blood tests before you start DUVYZAT and regularly during treatment to check your triglyceride levels.
  • Frequent watery loose stools (diarrhea) and vomiting. DUVYZAT can cause vomiting and moderate to severe diarrhea. If diarrhea occurs, you should keep track of the frequency and severity of your diarrhea symptoms, drink plenty of fluids, and contact your doctor.
  • If thrombocytopenia, increased triglycerides, or diarrhea cannot be managed, your doctor may change your dose or stop your treatment with DUVYZAT, if needed.

Before taking DUVYZAT, tell your doctor about all of your medical conditions, including:

  • any heart problems or medicines you take that could increase your chance for irregular heart rhythms.
  • any bleeding problems.

Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Taking DUVYZAT with certain other medicines may affect each other. Taking DUVYZAT with other medicines can cause serious side effects. Do not start or stop other medicines without talking to your doctor.

What are the possible side effects of DUVYZAT?

  • DUVYZAT can cause serious side effects, including changes in the electrical activity of your heart called QT prolongation. QT prolongation can increase the risk of developing a type of irregular heart rhythm known as Torsades de Pointes. Call your doctor right away if you feel faint, have an irregular heartbeat, feel dizzy, or lose consciousness. See the section titled “What is the most important information I should know about DUVYZAT?” for more information about side effects.

The most common side effects (occurring in >5% of DUVYZAT-treated patients) included diarrhea, abdominal pain, low platelet levels, nausea/vomiting, high triglyceride levels, elevated temperature/fever, muscle aches, rash, joint pain, fatigue, constipation and decreased appetite.

These are not all of the possible side effects of DUVYZAT. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Indication

What is DUVYZAT?

DUVYZAT is a prescription medicine for the treatment of Duchenne muscular dystrophy (DMD) in people 6 years of age and older. It is not known if DUVYZAT is safe and effective in children under age 6.

Please see full Prescribing Information and Medication Guide.